Small risk of osteoarticular infections in children with asymptomatic oropharyngeal carriage of Kingella kingae.

نویسندگان

  • Dimitri Ceroni
  • Victor Dubois-Ferrière
  • Rebecca Anderson
  • Christophe Combescure
  • Léopold Lamah
  • Abdessalam Cherkaoui
  • Jacques Schrenzel
چکیده

The aim of this study was to evaluate the absolute risk for children younger than 4 years of age with asymptomatic oropharyngeal carriage of Kingella kingae to sustain an osteoarticular infection. The rate of K. kingae carriage in the oropharyngeal mucosa was 9% among healthy children, and the risk for an asymptomatic carrier to develop an osteoarticular infection due to K. Kingae was estimated to be lower than 1%.

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منابع مشابه

Comparing the oropharyngeal colonization density of Kingella kingae between asymptomatic carriers and children with invasive osteoarticular infections.

Colonization of the oropharynx by Kingella kingae is currently considered to be a prerequisite for later development of invasive infections. However, the oropharyngeal K. kingae DNA bacterial load in children with osteoarticular infections caused by this microorganism is not different than that of asymptomatic carriers.

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Detection of Kingella kingae osteoarticular infections in children by oropharyngeal swab PCR.

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Identifying Reservoirs of Infections Caused by Kingella kingae: A Case-Control Study of Oropharyngeal Carriage of K. kingae Among Healthy Adults.

BACKGROUND Kingella kingae is currently recognized as a significant pathogen of the pediatric population. Nevertheless, the possibility for adults to serve as a reservoir of healthy carriers has not been studied. METHOD We conducted a monocentric transversal study on 228 healthy adults to define the carriage rate. Participants were recruited among the staff of a children's hospital, a populat...

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Kingella kingae Causing Septic Arthritis of the Knee in an Immunocompetent Adult

The bacterium Kingella kingae is a species of Gram-negative coccobacillus usually found in the oropharynx. This is an emerging pathogen reported to cause bacteraemia, endocarditis, and osteoarticular infections in children and endocarditis in the immunocompromised adult. However, there are few cases of isolated joint infections reported in the immunocompetent adult. Due to specific isolation te...

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Respiratory Colonization by Kingella kingae, Person-to-Person Transmission, and Pathogenesis of Invasive Infection

Increasing recognition of Kingella kingae as an important pathogen of early childhood in recent years has elicited interest in the study of the asymptomatic carriage of the organism, its dissemination in the human population, and the role played by colonization of the upper respiratory tract in the pathogenesis of K. kingae invasion of the skeletal system and the endocardium. Research has revea...

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عنوان ژورنال:
  • The Pediatric infectious disease journal

دوره 31 9  شماره 

صفحات  -

تاریخ انتشار 2012